Tuesday, December 27, 2011

Obamas go to church, dine in for Christmas in Hawaii (Reuters)

HONOLULU, Hawaii (Reuters) ? President Barack Obama spent a low-key Christmas Day with his wife and daughters in Hawaii, going to church and thanking U.S. troops for their service before hosting friends for dinner at the first family's rented beach house.

The Obamas started opening gifts around 8 a.m. on Sunday and then ate breakfast and sang carols together before heading to the chapel at the Marine Corps Base Hawaii for a Christmas service, the White House said.

Far from Washington officialdom, and making the most of a bright, warm day, Obama dressed casually in a polo shirt and khaki pants to church and Michelle and their daughters Sasha and Malia wore summer dresses.

After a few hours back at their multi-million-dollar temporary home, the president and Michelle Obama returned to the base to shake hands, hold babies and pose for pictures with hundreds of sailors and marines stationed there.

"In the evening, the First Family and friends will celebrate with a Christmas dinner at home," a White House official said. Sam Kass, the White House chef, is spending the holidays with the Obamas and was expected to do the cooking.

(Reporting By Travis Quezon; Writing by Laura MacInnis; Editing by Todd Eastham)

Source: http://us.rd.yahoo.com/dailynews/rss/obama/*http%3A//news.yahoo.com/s/nm/20111226/ts_nm/us_usa_obama

school closings lindsey vonn lindsey vonn josef stalin

Storify: See #Christmas eve in Rome, Bethlehem, Vienna. A beautiful slideshow from around the world. http://t.co/PXe8WKuZ

  • Passer la navigation
  • Twitter sur votre mobile ? Cliquez ici m.twitter.com!
  • Passer cette ?tape
  • Connexion
Loader Twitter.com
  • Connexion
See #Christmas eve in Rome, Bethlehem, Vienna. A beautiful slideshow from around the world. storify.com/globaltvnews/c? Storify

Pied de page

Source: http://twitter.com/Storify/statuses/150980963160178688

houshmandzadeh houshmandzadeh bieber baby justin beiber dia de los muertos dia de los muertos david arquette

Monday, December 26, 2011

Tournament of THG Semifinals: Robert Pattinson vs. Miley Cyrus!


Welcome back to the Tournament of THG, where fans vote on the most popular star of 2011! The concept is simple: Pick your favorite of the two stars in each poll. Done.

After four sometimes bruising second round matchups, the semifinal round begins now, with Robert Pattinson taking on Miley Cyrus for the right to make the finals.

Miles cruised into the final four with a big win over Kate Middleton, while the Twilight hunk triumphed over Pippa, Kate's sister, by a considerable margin as well.

Who will advance to the championship round? VOTE below!

Again, your votes alone will determine the most popular star of the past year on THG. Here's a look at how the field shapes up as we gear up to begin this round:

Tournament of THG Bracket: Semifinals

Source: http://www.thehollywoodgossip.com/2011/12/tournament-of-thg-semifinals-robert-pattinson-vs-miley-cyrus/

vanessa bryant vanessa bryant kurt busch kurt busch nfl mock draft 2012 adam lambert incendiary

Sony: Buy $100 Gift Card, get $20 Gift Card Free FREE

Sorry, Readability was unable to parse this page for content.

Source: http://www.logicbuy.com/deals/sony-gift-card/35521.aspx

new york giants dallas cowboys giants denver broncos patriots mega millions steelers

Sunday, December 25, 2011

Report: Another Chinese activist charged with subversion amid government crackdown

BEIJING - A veteran Chinese activist has been charged with subversion, a human rights group said Saturday, after another dissident was jailed for nine years in a crackdown aimed at preventing Arab Spring-style democratic uprisings.

Chen Xi was arrested Nov. 29 and charged Friday in the southern province of Guizhou, the Information Center for Human Rights and Democracy said. The Hong Kong-based center said Chen, who left prison in 2005 after serving a 10-year sentence, was accused of writing 30 essays that incited subversion.

A man who answered the phone at the Guiyang Intermediate People's Court said he had no information about the case.

On Friday, activist Chen Wei was sentenced to nine years, also on subversion charges.

Communist leaders launched a sweeping effort to crush dissent early this year in response to anonymous online calls urging Chinese to imitate protests that toppled governments in North Africa and the Middle East.

Human rights activists have criticized the ruling party's use of vague subversion laws to jail its critics. Authorities began using the subversion law against activists after repealing a widely criticized law on counterrevolutionary activities.

Chen Xi, 57, was active in the 1989 Tiananmen Square pro-democracy protests and was sentenced to three years in prison, the Information Center said in a statement. It said he was jailed for 10 years in 1995 on charges of counterrevolutionary offenses.

After his release, Chen was the first activist to sign the Charter 08 manifesto calling for an end to one-party rule and advocating democratic reforms, according to the Information Center.

The charter's co-author, Liu Xiaobo, who also is imprisoned on subversion charges, was awarded the Nobel Peace Prize last year for his pro-democracy activism.

Also this week, a government conference on politics and law called for a struggle against "hostile forces at home and abroad" and "illegal religious activities" next year, according to the Information Center, which is run by a mainland activist who lives in Hong Kong.

"Human rights conditions will continue to worsen next year," the Information Center said.

China's communist leadership was spooked early this year when online messages called for a Chinese "Jasmine Revolution," the name of the uprising in Tunisia.

Even though few outright demonstrators responded to the protest calls, China launched one of its broadest campaigns of repression in years, rounding up dozens of bloggers, lawyers and intellectuals. Most have since been released.

Others rounded up include Beijing activist Wang Lihong, who was sentenced to nine months in jail in September for staging a protest on behalf of other activists, and Yang Qiuyu, a Beijing activist who was sentenced to two years of re-education through labor.

Chen Wei's sentence appears to be the heaviest meted out in the crackdown, said Wang Songlian, a researcher with Chinese Human Rights Defenders, a Hong Kong-based advocacy group.

On Saturday, the European Union ambassador to Beijing, Markus Ederer, expressed concern about the sentence.

"The delegation of the European Union to China is deeply concerned by news of the disproportionate sentence handed down to democracy activist Chen Wei," Ederer said. "The EU firmly upholds freedom of expression as a universal human right and we encourage political debate rather than the use of criminal law as a means to resolve diverging political opinions."

Chen Wei, 42, previously served time for participating in the 1989 protests and was sentenced to five years in 1994 for "counterrevolutionary propaganda and incitement."

Amnesty International called for Chen Wei's release, saying his sentence was "clearly retaliation" for his criticism of the Communist Party.

___

Associated Press writer Gillian Wong contributed.

Source: http://www.startribune.com/world/136173943.html

ny jets seahawks new york giants dallas cowboys giants denver broncos patriots

Study linking virus and chronic fatigue retracted

(AP) ? The journal Science is retracting a controversial 2009 report that linked chronic fatigue syndrome to a virus.

In an unusual move, Science is taking that step on its own. Normally, authors retract their own research papers when serious problems arise after publication.

But Science has lost confidence in the report and the validity of its conclusions, editor-in-chief Bruce Alberts writes in Friday's issue. He said most of the authors have agreed in principle to retract the paper, "but they have been unable to agree on the wording of their statement." A retraction signed by all the authors "is unlikely to be forthcoming," Alberts wrote.

The original paper, from scientists at the Whittemore Peterson Institute in Nevada and the National Cancer Institute, reported finding a virus called XMRV in blood cells of patients with chronic fatigue syndrome. That raised hope that a cause of the mysterious illness had been found.

But follow-up studies by other scientists found no evidence of such a link. Last May, Science published two reports suggesting the original finding was due to lab contamination.

At the time, Alberts published a statement declaring that the validity of the study was "now seriously in question."

Then in September, the authors retracted some of the data, citing contamination.

In his statement on the full retraction, Alberts said the authors had also acknowledged omitting important information about the study's procedures in an illustration of some lab results.

Robert Silverman of the Cleveland Clinic, one of the paper's 13 authors, said in a statement Thursday that he was pleased by the full retraction. He said he had sought one this summer after finding that blood samples were contaminated.

The Whittemore Peterson Institute is preparing a statement about the retraction, a spokeswoman said Thursday.

___

Online:

Science: http://www.sciencemag.org

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2011-12-22-Chronic%20Fatigue/id-4635387b16d6477794769d0b10c7f5a0

slither craigslist killer chattanooga joey lawrence joey lawrence loma prieta loma prieta

Saturday, December 24, 2011

Amazon Debuts Store To Recommend ?Best Of? Digital Books, Apps, Movies, Software, Music And More

Amazon.com_ Best of DigitalAmazon is making it easier for its users to discover recommended content today with the launch of a new 'best of' digital store, where consumers can find recommendations from Amazon?s team of editors on the year's best of movies & TV shows, music, video games, software, mobile apps, magazines and Kindle books and more. Basically, Amazon will recommend the best of any type of digital content that the company sells. Of course, the timing of the launch is meant to coincide with holiday shopping season, which has historically brought record sales of digital content for Amazon. Last year, from Christmas Eve through December 30, Amazon customers purchased over three times more digital content, including Kindle books, magazines, movies, TV shows, music, and digital games as compared to the weekly average for the year.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/SkyesLVDp80/

latin grammys ogopogo walmart black friday walmart black friday raiders vincent jackson veterans day

Crowd gathers in San Rafael for Mill Valley church's toy giveaway

Three-year-old Reliy Cacluh carries a new toy he received from Big God Ministries during its annual toy giveaway at Pickleweed Community Center in San Rafael on Tuesday. (IJ photo/Alan Dep)

More than 100 adults and children gathered in San Rafael's Canal neighborhood Tuesday afternoon for a Mill Valley church's annual toy giveaway.

Big God Ministries volunteers unloaded some 2,000 toys from a U-Haul truck, organizing the play things by age and gender on folding tables at Pickleweed Park Community Center.

"My message is, 'Do something for somebody you don't know ? love them without that drama,'" said David Hall, pastor of the Mill Valley-based nondenominational Christian congregation.

Hall said his church distributed about 800 stuffed animals, board games, Barbie dolls and other toys in Marin City on Monday.

Hall, 49, grew up in Marin City with a single mother raising six children

Pastor David Hall of Big God Ministries talks to kids and their parent gathered for the ministry's annual holiday toy giveaway at Pickleweed Community Center in San Rafael. (IJ photo/Alan Dep)

with government assistance. He said he always appreciated it when people came to his neighborhood to do good.

For about 15 years, Hall worked as a football coach at Tamalpais High School and wasn't religious until a 14-year-old student on his team died of a brain tumor several years ago.

The experience inspired Hall, who also runs a car detailing business, to start Big God Ministries.

The church collects presents and cash donations for its Christmas toy giveaways and Thanksgiving turkey giveaways all year, Hall said.

Donela Lopez, 26, was waiting in line with her two daughters, ages 3 and 9 months, 15 minutes before church members arrived. Lopez said her husband works in a restaurant but has seen his income fall

due to the economy ? and buying gifts for the children remains challenging.

Sisters Lebi and Judith Alvarez were also at the event with their families, hoping to find nice children's gifts.

"They help many people," Lebi Alvarez said, speaking in Spanish. "They're the only ones who come to help out."

Volunteer Roland Carr, of Corte Madera, said he taught Hall mathematics in the mid-1970s at Tamalpais High and comes to help during the Thanksgiving and Christmas giveaways.

"It's

Donated toys were given away by the Big God Ministries. (IJ photo/Alan Dep)

nice to be able to give," Carr said. "The community has been good to me."

Contact Jessica Bernstein-Wax at jbernstein-wax@marinij.com

Source: http://www.marinij.com/millvalley/ci_19588080?source=rss

rocky horror picture show rutgers risky business weather nj weather nj nyc weather nyc weather

Friday, December 23, 2011

EU banks grabbing up ECB loans (Americablog)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/177802943?client_source=feed&format=rss

tom bradley penn state riot penn state riot state college pa wilson ramos kidnapped mcqueary mike mcqueary

Q Knot Reusable Cable Ties Keep Everything Tidy Without the Need for Scissors [Video]

Q Knot Reusable Cable Ties Keep Everything Tidy Without the Need for Scissors Zip ties are a pain, even the reusable velcro ones. These rubber cable ties will keep your cables neat without the need to wrestle them free later on.

Zip ties are great for keeping your cables organized and put away, but you need to cut them up if you ever want to get your cables out. Not only is this annoying, but depending on how often you need to get at your cables, it can end up costing you more in the long run. Even the reusable velcro-based ties are awful, requiring the jaws of life to pull apart. The Q Knot rubber cable ties are a much better solution for creating that perfect cordless workspace, since you can pull them apart easily and reuse them whenever you want. They're about $9 for a pack of 25 in three different sizes. Hit the link to check them out.

Q-Knot Pro Reusable Cable Ties | via Make

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/TazJVNCDn6I/q-knot-reusable-cable-ties-keep-everything-tidy-without-hassle-or-the-need-for-scissors

jim thome fun fun fun fest fun fun fun fest move your money alabama vs lsu alabama vs lsu robert schuller

Monday, December 19, 2011

Film reveals Paris crackdown of 1961 Algeria protest (Reuters)

DUBAI (Reuters) ? When Yasmina Adi got access to archives documenting the 1961 repression of Algerian protesters in Paris, she was shocked to uncover a trove of material relating to gaps in the story of one of the most contested events in recent French history.

As Algeria's battle for independence spilled into France, Paris police chief Maurice Papon ordered police to crack down on thousands of Algerian protesters who defied a curfew on October 17 1961. Dozens of bodies were later pulled from the River Seine.

Papon, who died in 2007, was the only French Nazi official to be convicted for his role in the deportation of Jews during World War Two. France has acknowledged the deaths of 40 people in the 1961 incident, but Adi says her research suggests it was much worse.

"This period remains a blank page. France doesn't recognize October 17 in school history books, it is not mentioned. Nothing you saw is in textbooks," Adi, who is of Algerian origin, said after "Here We Drown Algerians - October 17, 1961" aired at the Dubai International Film Festival this week.

"The people you saw are getting old, so this is an attempt to maintain the historical memory."

The documentary is narrated through the testimony of Algerians dragged off the streets by police and uses archive footage showing haunting images of thousands held in detention centers, transported in buses and sitting in planes during deportation.

A media campaign branded the protesters as Muslim terrorists, Adi's film says.

Some, such as Hadda Khalfi, one of the main interviewees who explains how her husband disappeared never to return, have never received an apology or compensation from the state.

"I managed to (access) the archives of the police department and state archives, which even some historians have not got permission to see. Then I asked myself what security bodies were there, and I found they all had their own archives," Adi said.

"It was the same for the filmed material... sometimes I noticed there were two people taking photos, so I said I have to go find them," she added.

"So I pieced together each part, when they put the Algerians on buses, when they detained them at the police department, the unseen photos from the Palais du Sport, the expulsions, the women's protest. At a certain point I said to myself 'wow'."

The true number of those who died may never be known.

"It's difficult to establish a figure. Some say 100, some say 200, some say 400, it's complicated. The police prefecture has a list of dead but these lists are not trustworthy," Adi said. "We could say around more than 1,500 were expelled."

GRAFFITI

Adi took the title for the film from graffiti daubed on a bridge over the Seine on October 28 1961 and caught on camera before the authorities could remove it. The words and the image she says dropped out of France's collective consciousness for decades.

She says France's unwillingness to offer more public recognition of what happened in those days contrasts with France's championing of Arab Spring causes such as Libya, which was taken up by President Nicolas Sarkozy and Bernard Henri-Levy, a prominent public intellectual in France.

"Sarkozy has said a few weeks ago why should Turkey be in Europe? If you Turks want to be in Europe you have to recognize the Armenian genocide. Before giving lessons to others, France ought to look at itself in history," she said.

"As citizens we should not allow ourselves to be manipulated by methods, images, language, because they cross time and governments take up the same methods and language."

France has had a complex relationship with Algeria since it was forced to give up a colony it ruled for 132 years in 1962 after a bitter war. Sarkozy has refused to apologize for Algerian dead.

France considered Algeria an integral part of the French state and more than 1 million French fled the country in the months before Algeria finally became independent.

Adi said she was surprised to see large audiences of young French people attending the screenings of her film in France when it was released in October.

"There were few Algerians but many French at the screenings, because many young people in particular are rediscovering the past and realizing it's not an Algerian problem but a Franco-Algerian problem," she said.

(Writing by Andrew Hammond, editing by Paul Casciato)

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/nm/20111217/film_nm/us_algeria_film

los angeles clippers charlize theron telenav telenav wade phillips wade phillips new orleans hornets

Sunday, December 18, 2011

Gingrich spends weekend in Washington

Republican presidential candidate former House Speaker Newt Gingrich speaks during a Republican presidential debate in Sioux City, Iowa, Thursday, Dec. 15, 2011. (AP Photo/Eric Gay, Pool)

Republican presidential candidate former House Speaker Newt Gingrich speaks during a Republican presidential debate in Sioux City, Iowa, Thursday, Dec. 15, 2011. (AP Photo/Eric Gay, Pool)

(AP) ? Just two weekends remain before the Iowa caucuses and Newt Gingrich, the Republican leading in the presidential race there, is spending this one about 1,000 miles away in Washington.

Periodic down time is not unusual for candidates who generally maintain a chaotic pace on the campaign trail.

But Gingrich is among the only candidates in a crowded and constantly evolving field to spend three full days away from voters less than 20 days before the first stop on the path to the Republican presidential nomination.

His chief rival, Mitt Romney, will spend Saturday in South Carolina ? a state Gingrich has high hopes for ? showcasing his latest high-profile endorsement, from South Carolina Gov. Nikki Haley.

By contrast, Gingrich will spend part of Saturday watching his wife, Callista, perform at a Christmas concert in northern Virginia. He also plans a morning conference call for reporters to present his criticism of the federal judiciary and how he would, as his campaign puts it, "bring federal courts back within the constraints of the U.S. Constitution."

In addition to the weekend Christmas concert, Callista Gingrich also has a book signing scheduled for Saturday in Virginia. On Sunday, Gingrich is scheduled to appear on CBS' "Face the Nation" and participate in a telephone town hall with tea party supporters.

Gingrich's campaign declined to comment on his schedule. He has struggled with the perception that he's unwilling to work as hard as some candidates to connect with voters.

Several staffers quit his campaign in June after questioning his commitment. He raised eyebrows at the time for spending two weeks on a luxury cruise through Greece and Turkey with his wife.

Gingrich's commitment to retail campaigning in early states has drawn criticism recently. He was the only candidate who didn't make time to meet with the New Hampshire conservative group, We the People PAC, which is led by leading local activist and recent Republican congressional candidate Jennifer Horn.

"I think that one of the most important parts of the primary process is candidates being willing to interact with voters," Horn said.

But strategically, time away from the media spotlight might be helpful, particularly for a candidate whose statements land him in trouble periodically.

"Although the political consultants wouldn't agree, I think you do have to pace yourself," said Rick Tyler, who was among the Gingrich staffers who resigned in June. "People get tripped up because they don't get adequate rest. And Newt's proven to the political consultants that he actually knows what he's doing."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2011-12-16-Gingrich/id-f1067a6ff3a744e5824b84785126f5cd

war of the worlds detroit lions bears bears lions terrelle pryor aids walk

Romney: I'm 'Ideal' for Tea Party (ABC News)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/175931410?client_source=feed&format=rss

new york giants kourtney and kim take new york anne hathaway news channel 5 nathan hale ohio state football kohls coupons

Saturday, December 17, 2011

Book Review : The Fossil Chronicles: How Two Controversial Discoveries Changed Our View of Human Evolution by Dean Falk

The Fossil Chronicles: How Two Controversial Discoveries Changed Our View of Human Evolution

A scientist who studies brain evolution examines fossil finds ? the Taung child and hobbits ? that are changing views of human evolution.

Univ. of California, 2011, 259 p., $34.95


Source: http://www.sciencenews.org/view/generic/id/336967/title/Book_Review__The_Fossil_Chronicles_How_Two_Controversial_Discoveries_Changed_Our_View_of_Human_Evolution_by_Dean__Falk_

payroll tax payroll tax lady gaga marry the night video lady gaga marry the night video pac 12 championship game pac 12 championship game hanukkah

Delve into the top ancient mysteries of the year

Peter Schmid / Lee Berger / Univ. of Wits.

The skeletal hand of an adult female Australopithecus sediba is nestled within a modern human hand. The analysis of the A. sediba bones led to what some experts called a "game-changing" view of evolution in 2011.

By Alan Boyle

Do archaeologists ever get tired of delving into ancient mysteries? One of my all-time favorite articles from The Onion is the one about the archaeologist who's fed up with "unearthing unspeakable ancient evils," but in real life,?you can't beat a good story about archaeology, paleontology?or paleoanthropology.

I'm?combining several?different scientific disciplines in?this end-of-year roundup of ancient mysteries. Archaeology has to do with studying?the peoples?of the past through an analysis?of the things they've left behind, ranging from the?bones of ?tzi the Iceman to?the pigeon nests built in a cave near Jerusalem. Paleontology is the branch of geology that focuses on the fossil record left behind by bygone organisms, including dinosaur dung.?And paleoanthropology focuses on our prehistoric ancestors and their relationships to other species.

It's been a busy year for archaeologists coping with the tumult that swept over Egypt and Libya ... for paleontologists debating where different species fit on the org chart for extinct organisms ... and for anthropologists analyzing how humans swapped DNA with heaven knows what other kinds of hominids. Here's a quick rundown, with?assists from the editors of Archaeology magazine and paleo-blogger?Brian Switek.

Archaeology
The top 10 discoveries of 2011, as rated by Archaeology, include revelations about these ancient mysteries:

I would add two late-breaking stories to the mix: one about the mysterious markings on the floor of an ancient complex in Jerusalem, and another about long-hidden 16-foot-wide pits in the ground near Stonehenge.

Paleontology
I asked Switek to help me sort through the year's top stories in paleontology, and he was kind enough to send this recap:

"Last year the big news was that paleontologists had restored the colors of two feathered dinosaurs. This year, there doesn't seem to be any major story that competes. But that's not to say that nothing significant happened in 2011. Here's a rundown of what I thought was interesting and important.

"Dinosaur growth: Over the past few years, paleontologists have been tussling over how many dinosaur species we have collected so far. The great Triceratops-Torosaurus debate of 2010 really brought this ongoing argument into focus, and there were several 2011 papers which continued the conversation. Early in the year paleontologist Andy Farke criticized the 'Torosaurus as Triceratops' hypothesis, and a reply to his reply has just appeared. Likewise, paleontologists suggested that the hadrosaur Anatotitan and the tyrannosaur Raptorex were really just growth stages of already-known dinosaurs (the latter being similar to Tarbosaurus, a juvenile of which was also described this year)." [Here's another take on the tussle over Triceratops.]

"Dinosaur senses: Two big papers - published at about the same time - probed dinosaur senses. One focused on smell, and the other vision. Studies like these represent our broadening understanding of dinosaur biology. It's not all about naming new species." [Learn more about the smell and night vision research]?

"Archaeopteryx: This year marked the 150th anniversary of when Archaeopteryx was discovered. The year has been full of ups and downs. Even though an 11th specimen of the feathered dinosaur was announced, a ballyhooed paper proposed that the creature was not an early bird but rather a non-avian dinosaur more distantly related to the first birds." [Here's more ballyhoo about the claim that Archaeopteryx wasn't a bird.]

"New species: New dinosaurs are named just about every week, but there were at least two that caught my eye. One was Brontomerus - a sauropod whose name translates to "thunder thighs" - and Teratophoneus, a short-snouted tyrannosaur. (I just realized that both were found in Utah, though, so perhaps I have a bias for my adoptive state!)" [Learn more about "Thunder Thighs"?as well as other?ancient wonders?in Utah.]?

"Other paleo: I usually don't cover the really big stories - I like to root around for tales no one is telling - but a few studies from this year got my attention."

? Plesiosaurs gave birth to live young
? Marsupial "wolf" hunted more like a cat
? Late-surviving predator was similar to those that swam the Cambrian
? Earliest saber-toothed herbivore found
? Ammonoids trapped parasites in pearls
? Cache of fossil feathers found in amber
? Woolly and Columbian mammoths may have interbred

Paleoanthropology
To round out this big?list, here are a few of the tales of human ancestors that caught my eye over the past year:

That's more than?30 tales of ancient mysteries to ponder. Which ones do you find most intriguing, or are there other tales we've missed? Feel free to weigh in with your comments below.


Alan Boyle is msnbc.com's science editor. Connect with the Cosmic Log community by "liking" the log's Facebook page, following @b0yle on Twitter and adding the Cosmic Log page to your Google+ presence. You can also check out "The Case for Pluto," my book about the controversial dwarf planet and the search for new worlds.

Source: http://cosmiclog.msnbc.msn.com/_news/2011/12/15/9478098-the-top-ancient-mysteries-of-2011

jason witten ucla vs usc rich rodriguez rich rodriguez the muppet movie the muppet movie mars rover

Friday, December 16, 2011

Judge to consider challenge of Utah bigamy law (AP)

SALT LAKE CITY ? A polygamous family made famous on a reality television show is asking a Utah federal judge not to block their challenge of the state's bigamy law.

Kody Brown and wives Meri, Janelle, Christine and Robyn filed a lawsuit in Salt Lake City's U.S. District Court in July. Oral arguments in the case are set for Friday before U.S. District Judge Clark Waddoups.

The stars of the TLC show "Sister Wives" said the law is unconstitutional because it prohibits them from living together and criminalizes their private sexual relationships.

Under Utah law, people are guilty of bigamy if they have multiple marriage licenses, or if they cohabitate with another consenting adult in a marriage-like relationship.

Formerly of Lehi, the Browns and their 17 children moved to Nevada in January after police launched a bigamy investigation. The Browns practice as part of their religious beliefs.

Oral arguments in the case are set for Friday in Salt Lake City's U.S. District Court.

It's not clear when Waddoups will rule.

State prosecutors contend the Browns ? who haven't been charged ? aren't facing any real harm because the state has rarely prosecuted individuals for bigamy without also prosecuting for other crimes, such as underage marriages, sexual abuse or welfare fraud.

"They have not been warned that if they do not cease to engage in their polygamous relationships that legal actions will be taken against them," Assistant Utah Attorney General Jerrold S. Jensen has said in court papers asking the judge to dismiss the case.

"And ? what is probably the tipping point ? there have been no arrests or prosecutions for the mere practice of polygamy in Utah in over 50 years."

A check of state court records by The Associated Press found at least two cases, however.

Bob Foster had three wives when he was arrested and charged with bigamy in 1974. He pleaded no contest and was sentenced to six months in Jail. He was released after 21 days and ordered to serve five years of probation. A judge also said Foster was not allowed to live with his families. Foster died from cancer in 2008. He was still married to all three women.

Mark Easterday was arrested and charged with bigamy in 1999. Authorities were alerted to Easterday's multiple marriage by his first wife as part of a custody battle during their divorce. He ultimately pleaded no contest to adultery because the divorce was finalized before the bigamy case went to trial. Easterday was sentenced to probation.

Easterday, who left Utah and is currently married to two women, told The Associated Press he believes the Browns are right to fear a bigamy prosecution.

"I know from experience that they do prosecute," Easterday said. I think they should change the law over the entire country. Why it is that in some places a woman and a woman can be married, but a man can't have another wife?"

Polygamy in Utah and across much of the Intermountain West is a legacy of 19th century Church of Jesus Christ of Latter-day Saints. Mormons abandoned the practice of plural marriage in the 1890s as a condition of Utah's statehood. The church now excommunicates members found engaging in polygamy.

An estimated 38,000 self-described Mormon fundamentalists continue the practice, believing it brings exaltation in heaven. Most keep their way of life a secret. In most cases, polygamous men are legally married to their first wives and marry subsequent brides only religious ceremonies.

Source: http://us.rd.yahoo.com/dailynews/rss/tv/*http%3A//news.yahoo.com/s/ap/20111216/ap_en_tv/us_sister_wives_lawsuit

tom bradley tom bradley penn state riot penn state riot state college pa wilson ramos kidnapped mcqueary

Kids' leukemia risk tied to dads' smoking (Reuters)

NEW YORK (Reuters Health) ? Children whose fathers smoked have at least a 15 percent higher risk of developing the most common form of childhood cancer, a new Australian study finds.

"Paternal smoking seems to be real" as a risk factor, said Patricia Buffler, a professor at the University of California, Berkeley, who was not involved in the current analysis.

"The importance of tobacco exposure and children's cancers has been overlooked until recently," Buffler told Reuters Health. "So I think this paper is important" in adding to the growing body of evidence.

The research team, led by Dr. Elizabeth Milne at the Telethon Institute for Child Health Research in Australia, surveyed the families of nearly 400 children with acute lymphoblastic leukemia (ALL).

Although ALL is the most common childhood cancer, it is still rare, affecting about three to five children out of every 100,000, according to the National Cancer Institute. More than 1,000 kids die of the disease every year.

The survey asked about the smoking habits of both parents.

Milne and her colleagues compared these families to the families of more than 800 children of similar ages who did not have leukemia.

They found that the mothers' smoking behavior had no impact on the kids' risk of developing the cancer.

But kids whose fathers smoked at all around the time of their conception were 15 percent more likely to develop leukemia. Those whose dads smoked at least 20 cigarettes per day around that time were 44 percent more likely to be diagnosed with the cancer.

A 15 percent increase in the risk of ALL would increase the number of cases from six out of every 200,000 children to seven out of every 200,000.

Of the nine earlier reports that the researchers used in their comparison with the current study, six of them also found an increased risk.

The findings make sense, Buffler said. "Tobacco smoke is full of toxins," including carcinogens, she said, "so it's not unlikely that you'd have damage" in the cells that produce sperm.

"Sperm containing DNA (damage) can still reach and fertilize an ovum, which may lead to disease in the offspring," Milne wrote in an email to Reuters Health.

The study did not prove that DNA damage in the sperm caused by smoking is responsible for the children's increased risk of cancer.

"The causes of ALL are likely to be multifactorial, and our findings relate to just one of the possible contributing factors," said Milne.

She added that her results are not intended to be used to place blame or make parents feel guilty.

Several other environmental factors are also tied to a greater chance of developing childhood leukemia, including ionizing radiation such as x-rays and the mother's exposure to paint or pesticides while pregnant.

Milne said that many of the studies regarding these potential causes have been small, and not conclusive.

Buffler is leading an international consortium of researchers tracking thousands of cases of childhood leukemia to determine the influence of environmental, genetic and other biological factors on developing the disease.

SOURCE: http://bit.ly/snq3sL American Journal of Epidemiology, online December 5, 2011.

Source: http://us.rd.yahoo.com/dailynews/rss/cancer/*http%3A//news.yahoo.com/s/nm/20111214/hl_nm/us_kids_leukemia

kelly slater kelly slater palindrome palindrome asana als disease brittany norwood

Wednesday, December 7, 2011

Is climate change altering humans' vacation plans?

Tuesday, December 6, 2011

Plants' and animals' seasonal cycles, such as flowering dates and migration patterns, have shifted in recent decades due to climate change.

Now a new study seems to indicate that some human weather-related behavior also is being influenced by global warming.

Researchers from the University of North Carolina at Chapel Hill found peak attendance in U.S. national parks that have experienced climate change is happening earlier, compared to 30 years ago.

According to the study recently published in the International Journal of Biometeorology, of the nine parks that experienced significant increases in mean spring temperatures since 1979, seven also saw shifts in the timing of peak attendance. For example, peak attendance at Grand Canyon National Park shifted from July 4 in 1979 to June 24 in 2008. Over the same period of time at Mesa Verde National Park, peak attendance changed from July 10 to July 1. The average shift was four days.

In contrast, of the 18 parks without significant temperature changes, only three exhibited attendance shifts.

"While the public continues to debate whether global warming is real, it appears that they are already adjusting their behavior," said Lauren Buckley, Ph.D., an assistant biology professor in the College of Arts and Sciences. "Visiting parks earlier may not be a big deal, but it may serve as a bellwether for more severe human adjustments required to cope with climate change."

"We can't say for sure that global warming is causing this swing in visitation trends," Buckley said. "But this discovery does complement rapidly accumulating evidence showing how other organisms have had to alter their behavior in response to climate change.

"National and state park agencies may need to plan for shifts in when users and tourists visit, as well as how wildlife respond to changes in the environment."

She acknowledged that other factors ? such as population changes, economic trends, park popularity and travel costs ? influence park visitor numbers. However, those elements are more likely to have an impact on total annual visits, rather than affect the timing and size of trends at the monthly and seasonal scale, as observed in this study.

She noted that the findings highlight a long-term, chronic shift in human behavior. Existing studies related to global warming and human behavior have mainly focused on the potential impact of extreme events and disasters, such as droughts and floods.

Meanwhile, Buckley also is investigating whether climate change is driving alterations in other aspects of human behavior, from consumption of certain types of seasonal foods to shifts in birth rates. Her analyses are ongoing.

###

University of North Carolina at Chapel Hill: http://www.unc.edu

Thanks to University of North Carolina at Chapel Hill for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 29 time(s).

Source: http://www.labspaces.net/115769/Is_climate_change_altering_humans__vacation_plans__

asu football arkansas lsu storage wars storage wars millionaire matchmaker millionaire matchmaker shawshank redemption

Tuesday, December 6, 2011

A New Low for Borders: Selling IP Addresses for $12 [Borders]

Like a haggard crackhead selling its socks, bankrupted Borders has resorted to selling things that don't actually exist. That's right—the company that once sold Ulysses and Jane Eyre is now hawking its collection of IP addresses. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/70YvELmxKQE/a-new-low-for-borders-selling-ip-addresses-for-12

scott disick kourtney kardashian kourtney kardashian lipitor lipitor kourtney kardashian pregnant again kourtney kardashian pregnant again

Iran downs a U.S. drone: Is 'all-out war' next? (The Week)

New York ? Tehran claims to have taken out a top-secret spy plane, potentially bringing a showdown over Iran's nuclear program closer

Over the weekend, as Iran claimed to have?shot down one of the U.S. military's RQ-170 stealth drones, Washington confirmed that an unmanned drone had indeed vanished on a mission in Afghanistan near the Iranian border. The incident ? a very serious one if it put sensitive technology in Iran's hands ? will surely only increase tensions between Iran and the West, which is imposing sanctions and possibly sabotaging Iranian military sites to get Tehran to end its apparent quest for nuclear weapons. Is the drone downing a sign that "all-out war" with Iran is inevitable?

Yes. The covert war could escalate: The United States, in cooperation with Israel, is not merely?headed for war with Iran, says Michael Hirsh at National Journal. The shooting has already begun. This weekend's events ? the alleged drone downing and a bombing near the British embassy in Bahrain ? were just the latest proof that the West is "engaged in a covert war against Iran's nuclear program," and that Iran "is retaliating with greater intensity than ever."?Let's face it: "It's entirely possible the covert war could escalate into a real one."
"Has the war with Iran already begun?"

No. The world doesn't want war: "Despite the uptick in signs of escalation," says Tony Karon at TIME, "the standoff over Iran's nuclear program is stuck in business-as-usual mode." Yes, the U.S., Israel, and their closest Western allies see Tehran's dreams of building an atomic bomb as "an urgent strategic security threat," but the rest of the world doesn't even want to tighten sanctions. "Expect the drumbeat of war to continue, for now" ? but I'd be surprised if we heard "a crescendo anytime soon."
"Despite downed U.S. drone claims, Iran war talk may be overblown"

We'll know soon enough: "It appears Iran plans to retaliate," says "Tyler Durden" at Zero Hedge. Its military has already threatened to respond to what it calls a provocative violation of its airspace. The USS John C. Stennis super-carrier is already within shooting range in the Arabian Sea. Nobody knows for sure what will happen next, but it "looks like life for the Stennis boys is about to get exciting."
"Iran military shoots down U.S. drone, threatens response"

View this article on TheWeek.com
Get 4 Free Issues of The Week

Other stories from this topic:

Like on Facebook?-?Follow on Twitter?-?Sign-up for Daily Newsletter

Source: http://us.rd.yahoo.com/dailynews/rss/oped/*http%3A//news.yahoo.com/s/theweek/20111205/cm_theweek/222119

the waltons the waltons weta weta rudolph the red nosed reindeer rudolph the red nosed reindeer adam carolla

Monday, December 5, 2011

Putin's party losing support in parliamentary vote

CAPTION CORRECTION CORRECTS THE NAME OF PHOTOGRAPHER - Prime Minister Vladimir Putin, with the emblem of the United Russia party in the background, visits the United Russia party headquarters in Moscow, Saturday, Dec. 4, 2011. Exit polls cited by Russian state television showed Prime Minister Vladimir Putin's party with less than 50 percent of the vote in Sunday's parliamentary elections, a significant drop reflecting Russians' growing weariness with his rule. (AP Photo/RIA Novosti, Alexei Nikolsky, Pool)

CAPTION CORRECTION CORRECTS THE NAME OF PHOTOGRAPHER - Prime Minister Vladimir Putin, with the emblem of the United Russia party in the background, visits the United Russia party headquarters in Moscow, Saturday, Dec. 4, 2011. Exit polls cited by Russian state television showed Prime Minister Vladimir Putin's party with less than 50 percent of the vote in Sunday's parliamentary elections, a significant drop reflecting Russians' growing weariness with his rule. (AP Photo/RIA Novosti, Alexei Nikolsky, Pool)

Elizaveta Semenova is helped by her daughter to fill in a ballot paper at her home in the village of Oster, 380 km (237 miles) west of Moscow, Sunday, Dec. 4, 2011. The ballot box has a sign reading: "Election" and the Smolensk region emblem. Russians cast their ballots with muted enthusiasm in national parliamentary elections Sunday, a vote that opinion polls indicate could water down the strength of the party led by Prime Minister Vladimir Putin, despite the government's relentless marginalization of opposition groups. (AP Photo/Sergei Grits)

Russian soldiers stand in line at a polling station in Moscow, Russia, on Sunday, Dec. 4, 2011. Russians cast their ballots with muted enthusiasm in national parliamentary elections Sunday, a vote that opinion polls indicate could water down the strength of the party led by Prime Minister Vladimir Putin, despite the government's relentless marginalization of opposition groups. (AP Photo/Alexander Zemlianichenko Jr)

Russian Prime Minister Vladimir Putin casts his ballot at a polling station in Moscow, Russia, Sunday, Dec. 4, 2011. Russians cast their ballots with muted enthusiasm in national parliament elections on Sunday, a vote that opinion polls indicate could water down the strength of the country's dominant party. (AP Photo/Ivan Sekretarev)

Russian Prime Minister Vladimir Putin greets journalists after voting at a polling station in Moscow, Russia, Sunday, Dec. 4, 2011. Russians cast their ballots with muted enthusiasm in national parliament elections on Sunday, a vote that opinion polls indicate could water down the strength of the country's dominant party.(AP Photo/RIA Novosti, Alexei Nikolsky, Pool)

(AP) ? Prime Minister Vladimir Putin's party was struggling to reach 50 percent in Russia's parliamentary election, polls and official results showed Sunday, suggesting Russians were wearying of the man who has dominated Russian politics for more than a decade.

Rival parties and election monitors said even this figure was inflated, alleging ballot-stuffing and other significant violations at the polls. Many expressed fears that the vote count would be manipulated.

Putin wanted to see his United Russia party do well in the election as a sign of public support for his return to the presidency in a vote now three months away ? one that he is still expected to win easily.

Putting a positive spin on the disappointing returns, Putin said "we can ensure the stable development of the country with this result," but he appeared glum and limited his remarks to two sentences.

Despite the setback, he was still expected to win the March presidential election and reclaim the position he held from 2000 to 2008. Putin has systematically destroyed any potential challengers. And most Russians do not see any credible alternatives, despite growing dissatisfaction with his strongman style, pervasive official corruption and the gap between ordinary people and the superrich.

United Russia held a two-thirds majority in the outgoing State Duma, which allowed it to change the constitution unchallenged. But it is increasingly disliked, seen as representing a corrupt bureaucracy and known to many as the "party of crooks and thieves."

The Communist Party appeared to be benefiting from the protest vote, with exit polls and the early returns predicting it would get nearly 20 percent, up from less than 12 percent four years ago.

The first official results with more than 25 percent of the vote counted showed about 47 percent for United Russia, compared to 64 percent in 2007. This was in line with an exit poll conducted by the VTsIOM polling agency that had United Russia tallying 48.5 percent and another done by the FOM polling agency that had it winning 46 percent of the vote. The two polls were reported by the two state television channels.

Complete results were expected at 0600 GMT Monday (1 a.m. EDT).

Only seven parties were allowed to field candidates for parliament this year, while the most vocal opposition groups have been denied registration and barred from campaigning.

Several parties complained Sunday of extensive election violations aimed at boosting United Russia's vote count, including party observers being hindered in their work.

Communist chief Gennady Zyuganov said his party monitors thwarted an attempt to stuff a ballot box at a Moscow polling station where they found 300 ballots already in the box before the start of the vote.

He said incidents of ballot-stuffing were reported at several other stations in Moscow, Rostov-on-Don and other areas. In the southern city of Krasnodar, unidentified people posing as Communist monitors had shown up at polling stations and the real observers from the party weren't allowed in, Zyuganov said.

In Vladivostok, voters complained to police that United Russia was offering free food in exchange for promises to vote for the party.

Russia's only independent election monitoring group, Golos, has come under strong official pressure and its website was incapacitated by hackers on Sunday. Golos was still able to field more than 2,000 observers and they reported numerous violations, director Liliya Shibanova said.

She said many of the violations involved absentee ballots, including so-called "cruise voting" where people with the ballots are bused to multiple polling stations. In the Volga River city of Samara, observers and election commission members from opposition parties were barred from verifying that the ballot boxes were properly sealed at all polling stations, Shibanova said.

In Moscow, several journalists, including a photographer for The Associated Press, were briefly detained after taking pictures at a polling station.

Mikhail Kasyanov, a former prime minister during Putin's first presidential term, said he and other opposition activists who voted Sunday are under no illusion that their votes will be counted fairly.

"It is absolutely clear there will be no real count," he said. "The authorities created an imitation of a very important institution whose name is free election, that is not free and is not elections."

A few dozen activists of the Left Front opposition group tried to stage an unsanctioned protest just outside Red Square on Sunday, but were quickly dispersed by police, who detained about a dozen of them. Later in the evening, police said they arrested more than 100 other opposition demonstrators in the capital and about 70 in St. Petersburg when they attempted to hold an unauthorized rally.

The websites of Golos and Ekho Moskvy, a prominent, independent-minded radio station were down on Sunday. Both claimed the failures were due to denial-of-service hacker attacks.

"The attack on the site on election day is obviously connected to attempts to interfere with publication of information about violations," Ekho Moskvy editor Alexei Venediktov said in a Twitter post. The site was back up in the evening.

Golos, which is funded by U.S. and European grants, has come under heavy official pressure in the past week after Putin accused Western governments of trying to influence the election and likened recipients of Western aid to Judas.

Shibanova, the Golos leader, said its hotline was flooded Sunday with automated calls that effectively blocked it. Prior to the vote, many of the group's activists were visited by security agents, while Shibanova was held for 12 hours at an airport and forced to hand over her laptop.

The group had compiled some 5,300 complaints of election-law violations ahead of the vote, most of which were linked to United Russia. Roughly a third of the complainants ? mostly government workers and students ? said their employers and professors were pressuring them to vote for the party.

____

Jim Heintz, Nataliya Vasilyeva and Vladimir Isachenkov contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2011-12-04-EU-Russia-Election/id-cda5a1b8267b404db2ba28ccfbeb67f6

boxing andy dalton waterboarding corporal kelsey de santis corporal kelsey de santis ufc on fox juan manuel marquez

Video: Money in Motion

Insight on how to play the euro given all the headlines due out, with George Davis, RBC Capital Markets chief technical analyst.

Related Links:

Business & financial news headlines from msnbc.com

Source: http://video.msnbc.msn.com/cnbc/45525942/

ohio ohio john beck john beck mariska hargitay gmcr ohio news

Sunday, December 4, 2011

PFT: Suh loses appeal on suspension

IMG_4331_large_JPGAP

When the Ravens moved to Baltimore in 1996, the decided to conduct their training camp at nearby McDaniel College, in Westminster, Maryland.

This year, the lockout caused the Ravens to decide to move camp to the team?s facility.? They?ve decided to stay put for training camp in 2012.

?We?ve had long, serious discussions about this decision, and, when all is said and done, we believe we can better prepare for the season by holding training camp here as opposed to McDaniel College or any other facility away from here,? Ravens president Dick Cass said in a release issued by the team. ?We wanted to let the officials at McDaniel and at the hotel [Best Western] know as soon as we made the decision.?

The move, which Cass said wasn?t influenced by financial considerations, apparently is a product of the new labor deal.

?In 1996, Westminster was the best place for us to have training camp,? G.M. Ozzie Newsome said. ?How teams conduct training camp today is vastly different.? Our football needs and requirements are different.? The absence of two-a-days, how much space we need for the players and the meetings, the limited number of practices allowed by the new CBA, the importance of having an indoor field when the summer storms come ? all of that and more football-influenced factors, had me recommend to [owner] Steve [Bisciotti] and Dick that we hold camp here.?

Bisciotti apparently wrestled with the move.? ?From a football and team point of view, it?s an easy decision,? Bisciotti said.? ?Personally, this is difficult.? Some of my best memories as a kid are my family?s visits to the Colts? training camp in Westminster.? Part of my devotion to the game and the players who made it great and are heroes to many of us, started on those visits.

?We completely understand that this takes away an important part of our connection with our fans. I regret that,? Bisciotti added.? ?Hopefully, we can find other ways to continue this outreach.? We?ll have more to say on this as we develop these programs.?

It?ll be interesting to see whether other teams follow suit, abandoning the traditional training camp experience for the facility to which the players report to work throughout the year.? The reasons articulated by the Ravens should apply to every team that currently has an off-site camp.? Time will tell whether more and more of them come to that same conclusion.

Source: http://profootballtalk.nbcsports.com/2011/12/02/ndamukong-suh-loses-his-appeal/related

father of the bride bluebeard blue angels weather miami ohio state angus t. jones belgian malinois

Saturday, December 3, 2011

Lions' Suh crashes car in Portland; not injured

(AP) ? Police in Oregon say Detroit Lions defensive tackle Ndamukong Suh crashed his car into a tree in downtown Portland, but was not injured.

Police say Suh was not impaired and was cooperative with officers following the accident at about 1:15 a.m. Saturday. Suh lost control of the 1970 Chevrolet Coupe he was driving, which then hit a curb, light pole, drinking fountain and tree. His vehicle was towed from the scene.

Suh had two passengers in the vehicle. They were not injured.

Suh is a graduate of Portland's Grant High School. He was the NFL's 2010 defensive rookie of the year. On Tuesday, the league suspended him for two games for stomping the arm of Packers guard Evan Dietrich-Smith.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-12-03-FBN-Suh-Car-Crash-/id-7e6582d685384b2b85c0799f601dcefb

adrian peterson lee corso lee corso thanksgiving appetizers greg jennings thanksgiving recipes thanksgiving recipes

Diametric shift in 2 protein levels spurs Alzheimer's plaque accumulation

Thursday, December 1, 2011

A diametric shift in the levels of two proteins involved in folding, moving and cutting other proteins enables accumulation of the destructive brain plaque found in Alzheimer's disease, researchers report.

VPS35 is a protein that folds others into specific positions to unleash their functions. When levels are reduced as they are in aging, it unleashes the normally dormant BACE1, a protein responsible for beta amyloid plaque production, Georgia Health Sciences University researchers report in The Journal of Cell Biology.

When researchers modified a mouse model of Alzheimer's so that VPS35 production was essentially cut in half, BACE1 activity was increased, accelerating aging and development of related problems such as memory deficits and poor communication between brain cells as well as beta amyloid accumulation, said Dr. Wen-Cheng Xiong, developmental neurobiologist and Weiss Research Professor at GHSU and the study's corresponding author.

It was known that expression of VPS35 was down and BACE1 was up in Alzheimer's but the direct relationship was unknown, Xiong said. "We believe impaired function of VPS35 could be a risk factor for Alzheimer's and Parkinson's diseases," Xiong said. Discovering the relationship makes VPS35 a potential biomarker for the diseases as well as a target for new therapies to keep VPS35 elevated. The accelerated aging model Xiong developed and patented will enable these future drug studies.

This unhealthy balance causes cells to accumulate more waste than their recycling systems can handle. Additionally misfolded proteins end up in the wrong cell compartment where they form aggregates that eventually kill the cell. Being in the wrong place is what enables BACE1 activity to increase: it ends up stuck in a cell compartment called the endosome where high acidity levels activate the protein. As BACE1 becomes more numerous and active, it chops up more potentially productive proteins, turning them into garbage.

"Each protein knows its destination, lifespan and when it should be degraded; everything is controlled. With aging, their trafficking, their control system is disrupted," Xiong said.

Future questions include what reduces VPS35 levels, such as increased levels of reactive oxygen species that come with age, and whether exercise can help keep them up. 'We think VPS35 will be a new, hot and hopefully productive area for Alzheimer's and Parkinson's research," Xiong said.

The protein is classified a retromer. Retromers are important to recycling inside cells. While silent in healthy adults, BACE1 plays an important role in brain development.

###

Georgia Health Sciences University: http://www.georgiahealth.edu

Thanks to Georgia Health Sciences University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 47 time(s).

Source: http://www.labspaces.net/115648/Diametric_shift_in___protein_levels_spurs_Alzheimer_s_plaque_accumulation

tower heist reviews recursion amy schumer amy schumer ascii art ascii art andrew mason